Comparison of postpartum blood loss between intravenous oxytocin and intravenous methylergometrine maleate during third stage of labor
Phase 4
Completed
- Conditions
- ErgometrineOxytocinPostpartum hemorrhageThird stage of labor
- Registration Number
- TCTR20120000012
- Lead Sponsor
- Department of Obstetrics and Gynecology, Faculty of Medicine Ramathibodi Hospital.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
1. Parturients who had normal vaginal delivery
2. Singleton pregnancy
3. Gestational age 37-41 weeks
4. Newborn birth weighed equal or greater than 2500 grams with Apgar score at 1, 5 minutes equal or greater than 7.
Exclusion Criteria
Parturients who had complications during pregnancy and were hypersensitive to oxytocin and/or ergometrine.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postpartum blood loss 2 hours after baby birth Absorbable pad and blood collecting plastic bag
- Secondary Outcome Measures
Name Time Method side effects and complications of delivery 2 hours after baby birth A parturient’s record form
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie oxytocin and methylergometrine maleate in preventing postpartum hemorrhage during the third stage of labor?
How does the efficacy of intravenous oxytocin compare to intravenous methylergometrine maleate in reducing postpartum blood loss in the third stage of labor?
Are there specific biomarkers that can predict which patients will respond better to intravenous oxytocin or methylergometrine maleate for postpartum hemorrhage prevention?
What are the known adverse events associated with intravenous oxytocin and methylergometrine maleate use during the third stage of labor and how are they managed?
What are the potential advantages and disadvantages of using combination therapies involving oxytocin and ergot alkaloids like methylergometrine maleate for postpartum hemorrhage prevention?