Acute serotonergic modulation of brain regions and behaviors implicated in mood regulatio

Not Applicable

Completed

• Conditions: Effects of the antidepressant escitalopram in healthy volunteers; Mental and Behavioural Disorders

• Registration Number: ISRCTN10650334
• Lead Sponsor: Max Planck Institute for Human Cognitive and Brain Sciences

Brief Summary

2014 results in https://www.ncbi.nlm.nih.gov/pubmed/25242032 (added 16/12/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-12-31
• Study Start: 2020-03-10
• Last Update Posted: 30 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

1. 20-30 years of age
2. Naive to antidepressants

Exclusion Criteria

1. Current or past psychiatric diagnosis as assessed with SKID-I and SKID-II interview
2. Major head trauma or neurological disease, current or in history
3. Use of psychotropic medication or of recreational drugs
4. MRI contraindications such as metal implants, claustrophobia, pregnancy
5. Smoking
6. Irregular sleep/wake rhythm (e.g., regular nightshifts or cross timeline travel)

Study & Design

• Study Type: Interventional
• Study Design: Not specified