eedling technique with topical Latanoprost in treatment of hypopigmented burn scars
- Conditions
- Hypopigmented scar.Other disorders of diminished melanin formation
- Registration Number
- IRCT20111123008177N18
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Patients aged 15-50 years.
In two symmetrical regions of the body (focusing on the organs) having hypopigmented scars.
Willing to cooperate and follow-up on treatment and complete the informed consent form.
Patients who are pregnant, are planning to become pregnant, or are breastfeeding.
Those who have had severe systemic diseases in the past 6 months.
Concomitant diseases (diabetes, connective tissue disease, chronic kidney disease, cardiovascular disease) and any type of disease that can cause immune system dysfunction and delay wound healing.
Immunosuppressant drugs and corticosteroids.
History of the use of depigmented or pigmented products on scars during the past 3 months.
Have a history of allergy or high sensitivity to the compounds used in the study.
Smoking and alcohol consumption.
Since the onset of a lesion leading to hypopigmented or depigmented scars, only 6 months have passed.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Scar. Timepoint: Before intervention, 3 and 6 months after using the last dose of drops. Method of measurement: 0-4 scale (including resizing and colorimetric staining) and Vancouver Scar scale.
- Secondary Outcome Measures
Name Time Method Patient satisfaction. Timepoint: Before intervention, 3 and 6 months after using the last dose of drops. Method of measurement: Visual Analog Scale.;Cost. Timepoint: The end of the study. Method of measurement: Estimated cost of microneedling process and latanoprost drops.