A clinical trial to compare the effect of two sleep causing drugs namely etomidate and propofol-phenylephrine combination on heart rate and blood pressure in adult patients undergoing open heart surgeries
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: I052- Rheumatic mitral stenosis with insufficiency
- Registration Number
- CTRI/2022/02/039898
- Lead Sponsor
- Molli Kiran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
Adult ASA II-IV patients undergoing elective cardiac surgeries involving valve replacement and/or coronary artery bypass grafting surgeries who are willing to participate in the study.
Exclusion Criteria
1.Patients with known allergy to the study drugs
2.Emergency surgeries
3.Patients with anticipated difficult airway and patients who require more than 2 attempts or more than 30 seconds for direct laryngoscopy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure every 30 sec for the first ten minutes after inductionTimepoint: first ten minutes after anaesthesia induction
- Secondary Outcome Measures
Name Time Method number of extra doses of phenyl ephrine needed in both the groupsTimepoint: first ten minutes of induction