Perseveration in the development of Obsessive Compulsive Disorder: responses to mild, incidental doubt

Completed

Conditions: Obsessive Compulsive Disorder
obsessive neurosis
10002861

Registration Number: NL-OMON39534

Lead Sponsor: niversiteit Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 93

Inclusion Criteria

There are two patient groups. In the OCD patient group, participants will be included when they have a DSM-IV diagnosis of Obsessive Compulsive Disorder. In the anxiety-control group, participants will be included when they have a DSM-IV diagnosis of an anxiety disorder (non-OCD). All patients are allowed to use SSRI drugs, but not benzodiazepines, because these have a negative effect on ones reaction speed. The two patient groups and the healthy controls group will be matched at group level on gender, age and education level.

Exclusion Criteria

Individuals with psychotic disorders, drug abuse or non-fluency in Dutch will be excluded. Healthy controls will also be excluded when they have any current psychiatric disorder. As mentioned, patients who use Benzodiazepine drugs will be excluded.

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are level of uncertainty and checking behaviour.<br /><br>Level of uncertainty will be measured by asking the questions How certain did<br /><br>you feel when you reported target present* in the past trials?* and How<br /><br>certain did you feel when you reported target absent* in the past trials?* (9-<br /><br>point Likert scale; 1 = not at all, 9 = very much). Checking behavior will be<br /><br>measured by search time (average time participants spend searching through a<br /><br>display) and several eye movement measures (using eye tracking).</p><br>

Secondary Outcome Measures