The effects of perseveration in Obsessive Compulsive Disorder on semantic satiation and dissociative doubt
- Conditions
- Obsessive Compulsive Disorderobsessive neurosis10002861
- Registration Number
- NL-OMON36836
- Lead Sponsor
- niversiteit Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Patients will be included when they have a DSM-IV diagnosis of Obsessive Compulsive Disorder. Patients are allowed to use SSRI drugs, the use of SSRI's will be controlled for in the analysis.
Healthy controls will be age/education matched with the patients included in the study.
Subjects will be excluded if they are insufficiently proficient in the Dutch language, and/or if they are addicted to alcohol or drugs; and/or if they are under 18 years of age; and/or if they present symtoms form the psychotic spectrum. Patients who use benzodiazepine drugs will be excluded.
Healthy controls will also be excluded when they have any current psychiatric disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>First part: The main study parameters are the ratings of dissociative<br /><br>uncertainty of OCD patients after clinical perseveration or after<br /><br>non-perseverative behaviour.<br /><br><br /><br>Second part: The main study parameters are the participants* ratings of<br /><br>dissociative uncertainty, the intolerance of dissociative uncertainty and the<br /><br>degree of semantic satiation after perseveratively and non-perseveratively<br /><br>repeating words. Semantic satiation will be determined by measuring reaction<br /><br>times in the relatedness decision task.</p><br>
- Secondary Outcome Measures
Name Time Method <p>nvt</p><br>