Whole-body cryostimulation in sportsmen a study of the effect of cryogenic temperatures on oxidative stress and inflammation after the exercise

Completed

• Conditions: oxidative stress; inflammation; Inflammatory and Immune System - Normal development and function of the immune system; Musculoskeletal - Normal musculoskeletal and cartilage development and function; Injuries and Accidents - Other injuries and accidents

• Registration Number: ACTRN12618001711202
• Lead Sponsor: icolaus Copernicus University

Brief Summary

The subjects (n=87) were exposed to low temperatures (-130oC) and then a 40-minute exercise (80% HRmax). Blood for testing has been collected: before the start of the study, just after the whole body cryostimulation (WBC) session, after the exercise accompanied by cryostimulation and after the exercise without WBC. Antioxidant enzymes activity and thiobarbituric acid-reactive substances concentration, conjugated dienes and A and E vitamins levels, as well as creatine kinase, cytokines (IL-1beta, IL-6, TNF-alpha, TGF-beta1) and total lipid peroxides (LOOH) concentration were determined in the blood. It has been shown that CAT activity in sportsmen blood measured after exercise associated with cryostimulation was lower in comparison to the activity recorded after control examination. When taking into consideration various sport disciplines separately only for the volleyball players CAT activity was lower when it was measured after exercise preceded with cryostimulation than after control examination. After comparing impact of exercises preceded by WBC and physical effort without the WBC on IL-1a concentration in sportsmen blood, it was shown that IL-1a level is lower when exercises were preceded by cryostimulation. The single WBC cased decrease in IL-6 level in sportsmen blood. It also was shown that the concentration of this interleukin in the amateurs blood serum was lower than when exercise was preceded by cryostimulation in comparison with level after control examination.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2011-11-01
• Study Start: 2018-10-17
• Last Update Posted: 26 November 2018

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 64

Inclusion Criteria

Practising sport professionally or amateurishly.

Exclusion Criteria

Occurrence of any diseases.

Study & Design

• Study Type: Interventional
• Study Design: Not specified