The Influence of Cardiovascular Risk Factors on Electrocardiographically and Hemodynamics Responses to Treadmill Exercise Test in Asymptomatically Subjects: a Clinical Perspective (ERGO-RISC)

University of Sao Paulo1 site in 1 country400 target enrollmentAugust 30, 2023

ConditionsCardiovascular Diseases Cardiovascular Abnormalities Healthy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Cardiovascular Diseases
Sponsor: University of Sao Paulo
Enrollment: 400
Locations: 1
Primary Endpoint: ECG abnormalities and risk factors
Status: Completed
Last Updated: 11 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this observational cross-sectional study is to analyze the effect of cardiovascular risk factors in healthy and asymptomatic populations. The main questions it aims to answer are:

Does the combination of the presence of different risk factors increase the risk for abnormalities appearing on electrocardiograms, such as ischemia, arrhythmia, and hemodynamics effects during and at the peak of effort of treadmill exercise test?
What are the main differences observed in the recovery period? Participants will answer an anamnesis of risk factors such as sex, race, age, familiar history of coronary artery disease, overweight or obesity, smoking, stress, and physical activity practice and perform treadmill exercise test on Ellestad protocol. If there a comparison groups: Researchers will compare individuals with most risk factors with those without, to see the cardiovascular responses.

Detailed Description

The main outcomes broad the effect of simples and easy doccumented cardiovascular risk factors such as sex, race, age, familiar history of coronary artery disease, overweight or obesity, smoking, stress, and physical inactivity on electrocardiogram and hemodinamics abnormalities during and after exercise treadmill exercise test.

Registry

clinicaltrials.gov

Start Date

August 30, 2023

End Date

March 26, 2025

Last Updated

11 months ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Sao Paulo

Responsible Party

Principal Investigator

Pedro Gabriel Senger Braga

Ph.D.

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

•Subjects that can complete the treadmill exercise test with the Ellestad protocol with 6 minutes of recovery.

Exclusion Criteria

•Use of remedies for blood pressure, glycemia, cholesterol, and serum lipids;
•Symptomatically subjects;
•Electrocardiogram that are not able to be interpreted;
•Blood pressure in rest state ≥180 mmHg and ≥110 mmHg, for systolic and diastolic, respectively.