NCT00437177Unknown2 期
Relationship Between D2 Receptors SPECT and the Apomorphine Test in Patients With OH Dependence: Predictive Value for Relapse
适应症
相关药物
试验速览
- 阶段
- 2 期
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- To detertmine the agreement rate of the dopaminergic sensibility assessed by two different techiniques: the apomorphine test and and IBZM SPECT.
研究概览
简要总结
OH dependence is associated with DA receptor changes. Both, the apomorphine test and the D2Rec SPECt are usefull for monitoring DA receptor status. We aimed at studying whether DA receptor hypofunction, assessed by means of the apomorphine test and the D2Rec SPECT, is a marker of relapse in detoxified OH dependents patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •alcohol dependence
- •alcohol dependence length at least 8 years.
- •age 25 - 60 years
排除标准
- •other drug dependence (except nicotine dependence)
- •another major axis I psychiatric diagnosis
- •comorbid neurological disorder
- •comorbid cardiovascular disorder
- •comorbid metabolic disorder
- •brain injury
- •apomorphine allergy
- •iode allergy
- •diazepam allergy
结局指标
主要结局
To detertmine the agreement rate of the dopaminergic sensibility assessed by two different techiniques: the apomorphine test and and IBZM SPECT.
时间窗: 3 months
次要结局
未报告次要终点
研究者
研究点 (2)
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