Dopamine D2 and D3 receptors occupancy evaluation study of continuous antipsychotic drug administration by positron emission tomography
Not Applicable
- Conditions
- Schizophrenia
- Registration Number
- JPRN-UMIN000021175
- Lead Sponsor
- ippon Medical School
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 13
Inclusion Criteria
Not provided
Exclusion Criteria
- with past or current history of serious medical illness and/or brain organic diseases - subject who is contraindicated for the use of MRI - with past or current history ofsevere liver disease, kidney disease, heart disease, allergy, or severe drug allergy - contraindication for blonanserin - treated by electroconvulsive therapy within 3 months before the screening. - taking tandspirone at the screening. - subject who are judged as not suitable for participation in this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of the dopamine D2 and D3 receptor occupancy of antipsychotics will be assessed after taking antipsychotics for 2 weeks.
- Secondary Outcome Measures
Name Time Method blood concentration, MRI, neuropsychological test