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A study of the association of dopamine D1 and D2 receptor binding potentials in the brain with clinical features of patients with dystonia

Not Applicable
Conditions
dystonia
Registration Number
JPRN-UMIN000040130
Lead Sponsor
ational Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
25
Inclusion Criteria

Not provided

Exclusion Criteria

1) patients with dystonia 1. Subjects with organic brain complications/disorders 2. Subjects with substance-related disorders 3. Subjects with severe physical complications/disorders or a history of such conditions 4. Subjects with claustrophobia 5. Pregnant, possibly pregnant or lactating women 6. From the standpoint of radiation exposure from a nuclear medicine scan, subjects who have participated in other nuclear medicine scans as healthy volunteers in the 6 months prior to the start of this study 7. Subjects who are considered to be inappropriate for participation by doctors with responsibilities in this study 2) Healthy volunteers We exclude the data of the healthy volunteers who refused secondary use of their data for another clinical studies at the time of obtaining consent. Under the announcement of the secondary use in the homepage of National Institutes for Quantum and Radiological Science and Technology, we exclude the data of the healthy volunteers who underwent scans or examinations in the studies by 31 December 2019, if they refuse secondary use by 30 June 2020.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The associations between dopamine D1 and D2 receptor binding potentials evaluated by PET and clinical features of dystonia
Secondary Outcome Measures
NameTimeMethod
The associations between dopamine D1 and D2 receptor binding potentials evaluated by PET and brain structures evaluated by MRI of dystonia
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