NCT07138781已完成不适用
Role of Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain: A Randomized Controlled Trial
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Time to the 1st rescue analgesia
研究概览
简要总结
The aim of this study is to evaluate the role of ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years.
- •Both sexes.
- •American Society of Anesthesiology (ASA) physical status I-III.
- •Scheduled for open thoracotomy.
排除标准
- •Patients with neurological or intellectual disability.
- •Infection at the injection site.
- •Opioid addiction.
- •Allergic reaction to local anesthetics.
- •Coagulation abnormalities.
- •Drug abuse.
- •Pregnancy.
- •Severe liver and/or renal failure.
- •Severe cardiovascular problems.
研究组 & 干预措施
Group K
Experimental
Patients will receive 29 ml bupivacaine 0.25% + 1 ml ketamine (50 mg) as a study group.
干预措施: Ketamine (Drug)
Group C
Active Comparator
Patients will receive 29 ml bupivacaine 0.25% + 1 ml saline as a control group.
干预措施: 29 ml bupivacaine 0.25% + 1 ml saline (Drug)
结局指标
主要结局
Time to the 1st rescue analgesia
时间窗: 48 hours postoperatively
Time to the first request for the rescue analgesia will be recorded from end of surgery to first dose of morphine administrated.
次要结局
- Intraoperative fentanyl consumption(Intraoperatively)
- Total morphine consumption(48 hours postoperatively)
- Mean arterial pressure(Till the end of surgery (Up to 2 hours))
- Degree of pain(48 hours postoperatively)
- Heart rate(Till the end of surgery (Up to 2 hours))
- Incidence of adverse events(48 hours postoperatively)
研究者
Mohammed Said ElSharkawy
Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University
研究点 (1)
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