ongitudinal investigation of quantitative MR imaging marker in leg muscles in Morbus Pompe
Not Applicable
Recruiting
- Conditions
- E74.0Glycogen storage disease
- Registration Number
- DRKS00023874
- Lead Sponsor
- BG UK Bergmannsheil / Neurologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Ensured diagnosis of Morbus Pompe OR no neuromuscular disorders at all (healthy controls)
Exclusion Criteria
MR contraindications e.g. implants, respiratory insufficency
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method i)After finishing acquisition and evaluation of all participants for timepoint 1, we will perform initial cross sectional comparisons between LOPD patients and matched controls to reproduce our previous findings, of increased diffusivity in LOPD muscles with <10% fat.<br>ii)After finishing all acquisitions longitudinal analysis of quantitative parameters (diffusion, fat and T2) in LOPD patients and in controls, and the analysis of the interaction between the timespan and the population group will be performed<br>
- Secondary Outcome Measures
Name Time Method