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Influence of polymorphisms of adenosine A2 receptor and dopamine D2 receptor on mental calculations, blood pressure and pulse rate after intake of caffeine: a double-blind randomized placebo-controlled clinical trial.

Not Applicable
Conditions
Effect of caffeine
Registration Number
JPRN-UMIN000010360
Lead Sponsor
Department of Clinical Pharmacology, Faculty of Medical Science, Kyushu University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
500
Inclusion Criteria

Not provided

Exclusion Criteria

1. cardiovascular disease that should be treated 2. severe liver disease 3. severe renal disease 4. pregnant women and women suspected of being pregnant 5. severe allergic reaction and allergic reaction to caffeine 6. gastric ulcer 7. glaucoma 8. On medical treatment 9. Not appropriate to this study by other reasons

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change of the accurate number of mental calculation after intake caffeine 200 mg compared to decafe
Secondary Outcome Measures
NameTimeMethod
Change of blood pressure and pulse rate after intake caffeine 200 mg compared to decafe
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