The influence of Annexin A2 SNP (rs17845226) on von Willebrand factor secretion by endothelial cells

Completed

• Conditions: von Willebrand disease; VWD; 10064477

• Registration Number: NL-OMON42870
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

- Participant of the Nijmegen Biomedical Study (NBS) with informed consent to be contacted for further research.
- Homozygous or heterozygous for the Annexin A2 SNP rs17845226 (c.346G>T), or WT.

Exclusion Criteria

- No written informed consent for study participation obtained from the subject.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>This study is a laboratory driven study. The main study endpoint is the<br /><br>elucidation of the Annexin A2 dependent VWF secretion pathway. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N.A.</p><br>