Comparison of continuous paravertebral blockade (PVB) and continuous thoracic epidural analgesia (TEA) for analgesia following open renal surgery
- Conditions
- This study will involve the administration of levobupivacaine 0.25% and 0.125%, a local anaesthetic agent licensed for this purpose, into the epidural and paravertebral space, to provide postoperative analgesia for adults having open renal surgery. We aim to compare the analgesic efficacy of paravertebral and epidural blockage, for post operative pain in the first 24 post operative hours.MedDRA version: 9.1Level: LLTClassification code 10054711Term: Postoperative pain
- Registration Number
- EUCTR2008-004998-17-IE
- Lead Sponsor
- Department of Anaesethesia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Adults 18-80 years
Presenting for elective open renal surgery
ASA 1 to 3
Written informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Patient refusal
Contraindication to neuraxial blockade
Local infection at site of insertion
Allergy to levobupivacaine, fentanyl, paracetamol or morphine.
Sepsis
Severe kyphoscoliosis
Previous thoracic vertebral surgery
Systemic anticoagulation or coagulopathy
Uncontrolled hypertension
Uncontrolled Diabetes Mellitus
Severe liver or cardiac dysfunction
Inability to comprehend pain scoring system or perform spirometry
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method