Cardiac Stroke Volume at Rest and During Different Exercise Intensities

Not Applicable

• Conditions: Cardiac Function

• Registration Number: NCT04287114
• Lead Sponsor: Turku University Hospital

Brief Summary

The main aim of the present investigation is to study cardiac function in different exercise intensities in healthy human subjects. Two techniques will be used: cardiac ultrasound-derived stroke volume measurements and body impedance measurements. 20 healthy men (n=10) and women (n=10) aged 18-45 years will be investigated at rest and during exercise. All study procedures are non-invasive.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-02-25
• Study First Submitted QC: 2020-02-25
• Study First Posted: 2020-02-27
• Status Verified: 2021-02
• Study Start: 2021-02-08
• Last Update Submitted: 2021-02-08
• Last Update Posted: 2021-02-09
• Primary Completion: 2021-12-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Age 18-45
• BMI 18-30
• Resting Blood pressure < 140/90 mmHg
• Participation in regular exercise

Exclusion Criteria

• Acute illness
• Pregnancy
• Pace maker
• Artificial joint
• History of a cardiac event
• Insulin or medically treated diabetes
• Any chronic disease or condition that could create a hazard to the subject safety, endanger the study procedures or interfere with the interpretation of study results
• Abundant use of alcohol
• Use of narcotics
• Smoking of tobacco or consuming snuff tobacco
• Diagnosed depressive or bipolar disorder
• Abnormalities in resting ECG (revised by the study physician)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Cardiac stroke volume	1 min

Secondary Outcome Measures

Name	Time	Method
Ejection fraction	1 min
End-diastolic and end-systolic volumes	1 min

Trial Locations

Locations (2)

Turku PET Centre; 🇫🇮 Turku, Finland

University of Turku; 🇫🇮 Turku, Finland