A randomised controlled clinical trial on efficacy of Navaka Kashaya and Manjisthadi Tail in the management of Vicharchika with special reference to dry eczema

INTRODUCTION

In Ayurveda,various skin diseases have been described under the term Kushtha. Vicharchikais a type of kshudrakushtha ,characterized by skin eruption withdark discoloration, itching and profuse discharge, being involved of threedoshas with the dominance of kapha acc to Acharya charak. Authors like Vagabhatta, Madhavakara and Bhavamishrado agree with him whereas Sushruta,‘the father of surgery’ has mentionedthe symptoms as dryness of the skin with intensive itching and markedthickening of skin, with the dominance of pitta. Similarly difference ofopinion exists between the other texts like Kashyapa*,* Harita*,* Bhelaetc, However Allthe authors have concluded with the fact that itching and eruption are cardinal symptoms.

Vicharchikahas been included under raktapradoshaja vikara.Being a type of kustha, recurrence & chronic course is common. It isskin disease with predominance of kapha with clinical features like kandu,srava, pidika, shyavata, rookshata, raji, rujaand daha mainly in extremities. It has social impact, affectspsychological status and disturb the social life due to its appearance, severeitching disturbing the routine.

NEED OF STUDY

In maximum of cases, patientscome to ayurveda treatment after not getting satisfactory cure from  modern medicine, naturally by the time the disease has attend thechronic state , hence it is the need of the hour to find out safe andeffective medicine for Vicharchika on a long term and here comes the role ofAyurveda.

To overcome the problem ofhigh rate of recurrence,  this trial drughas been selected which is effective in destroying all types of kushthaas mentioned in the phalashruti of trial drugs .These drugs helps todestroy the samprapti of vicharchika (Eczema) due to its ushnavirya and katu-kashaya  rasaand enchances the cure rate to the patient of vicharchika and check itsrecurrence.

AIM: To evaluate and compare the efficacy of “Navaka Kashaya & ManjisthadiTail†in the management of Vicharchika w.s.r. to Dry eczema withStandard Control Drugs (Betamethasone oint. & Tab Hydroxyzine).

OBJECTIVE

·       Evaluation and comparisonof effect of trial drugs  on signs andsymptoms of Vicharchika with special reference to Dry Eczema.

·       Evaluation and comparisonof effect of trial drugs on  EASI Score.

·       Evaluation and comparisonof effect of trial drugs on Extent of impairment in QoL by using DLQI(Dermatology Life Quality Index)

RESEARCH QUESTION

Is there any difference ineffect between the trial drugs and standard control drugs in the management ofVicharchika with special reference to Dry Eczema?

HYPOTHESIS

**Null Hypothesis (H0):**There isno difference between the effect of Trial drug (“Navaka Kashaya and Manjisthadi Tailâ€) and standard controldrug(Betamethasone oint. & Tab Hydroxyzine) in the management ofVicharchika w.s.r to Dry Eczema.

Alternative Hypothesis:

(H1): There is difference between the effect of trial drug( “Navaka Kashaya and ManjisthadiTailâ€)  and standard control drug (Betamethasoneoint. &tab Hydroxyzine)  in themanagement of Vicharchika w.s.r. to Dry Eczema.