A Randomized Comparative Clinical Study of Lodhra Churna with Krishna Tila Kwatha and Shatapushpa Taila Matra Basti in the Management of PCOS

Phase 2/3

Not yet recruiting

Brief Summary: Polycystic Ovarian Syndrome (PCOS) is a major non-communicable health problem world wide in women of different age groups due to sedentary lifestyle, stress, strain and restlessness. *Artavakshaya* is seen in the many cases of PCOS. According to *Acharya* *Sushruta* in *Artavakshaya* menstruation is delayed, menstrual blood is scanty and associated with pain in Vagina. PCOS is also a disease of *Artavavaha* *Srotas* in which vitiated *Vata* and *Kapha* *Doshas* causing *Artavakshaya* or *Alpartava*. The features of PCOS may also be correlated with â€˜*Pushpaghnee Jataharini*â€™ that is described in Ayurvedic classics (*Kashyapa* *Samhita*) having the clinical features of futile ovulation (*V**rutha Pushpa*) and corpulent hairy cheek (*Sthula* *Lomasha ganda*). Lodhra due to its Medokaphahara, Yonidoshahara property and Antiandrogenic effect with Krishna Tila due to its artavajanana property and Shatapushpa due to its rituparvritani, yonishukravishodhani, pittavardhaka properties have been taken in the present study to rule out and compare their therapeutic efficacy in the management of Artavakshaya.

Recruitment & Eligibility

Inclusion Criteria

PCOS patients suffering from any of the two features in the following- Duration of flow less than 2 days.
Reduced quantity of flow (using less than 2 pads/day).
Patients suffering from atleast 2 consecutive cycles with Oligomennorhoea and/ or anovulation.
Patients having hirsutism.
Patient having mid body obesity.
Atleast one ovary showing PCO (diagnosed by USG).

Exclusion Criteria

Pregnant and lactating women.
Patient with BMI less than 19.
Systemic disorders like- uncontrolled diabetes mellitus, chronic liver disease, renal disorder, high blood pressure, hypo and hyperthyroidism.
Not associated with any organic reproductive system abnormalities (Excluded clinically and radiologically), pelvic inflammatory disease, hydrosalpinx, endometriosis, adenomyosis, fibroid uterus, carcinoma of reproductive organ.
Patients having physiological infrequent menstruation.
Woman taking Oral Contraceptive Pills.
Hb. less than 7 gm%.

Primary Outcome Measures

Name	Time	Method
To assess the effect of Shatapushpa Taila Matra Basti in Artavakshaya.	2 Months
Attainment of normal menstrual cycle length (21-35days).	2 Months
To study the detail aetiopathogenesis of Artavakshaya (PCOS) as per classical & modern text.	2 Months
Changes in the clinical features of Artavakshaya (PCOS).	2 Months
To assess the effect of Lodhra Churna with Krishna Tila Kwatha in Artavakshaya.	2 Months

Secondary Outcome Measures

Name	Time	Method
Improvement of Quality of Life	2 months

Locations (1): National Institute of Ayurveda, Jaipur
🇮🇳
Jaipur, RAJASTHAN, India
National Institute of Ayurveda, Jaipur
🇮🇳Jaipur, RAJASTHAN, India
Dr K Bharathi
Principal investigator
9492047131
baruhunt@gmail.com