THE EFFICACY OF PAROXETINE AND COGNITIVE-BEHAVIOURAL THERAPY IN THE TREATMENT OF LATE-LIFE PANIC DISORDER: A RANDOMIZED CONTROLLED TRIAL.
Completed
- Conditions
- 1. Panic disorder<br />2. aged<br /> 3. drug therapy<br />4. cognitive therapy<br />5. paroxetine.<br />(NLD: Paniekstoornis, ouderen, farmacotherapie, cognitieve gedragstherapie, paroxetine).
- Registration Number
- NL-OMON23124
- Lead Sponsor
- 1. Radboud University Nijmegen, Behavioural Science Institute, Nijmegen, the Netherlands: Prof. dr. C.A.L. Hoogduin, Dr. G.P.J. Keijsers;<br>2. GGz Nijmegen, Outpatient Department for Anxiety Disorders, NijmegenPO Box 7049, 6503 GM Nijmegen, the Netherlands.
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. Panic disorder with/without agoraphobia (DSM-IV-criteria);
2. >60 years.
Exclusion Criteria
1. The presence of severe psychiatric disorders (e.g. psychosis, major depression, bipolar disorder);
2. A severe somatic condition which would hinder appropriate application of CBT (e.g. severe cardiovascular disease);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Self-report instruments for anxiety cogntions and phobic avoidance: scores on the Dutch adaptations of the Agoraphobic Cognitions Questionnaire (ACQ) and the Mobility Inventory avoidance scale (MI).
- Secondary Outcome Measures
Name Time Method Self-report instruments for depression and general psychopathology. Depressive symptoms were assessed with the Dutch adaptation of the Beck Depression Inventory (BDI) and general psychopathology was assessed with the Dutch adaptation of the Symptom Checklist (SCL-90).