To assess and compare effectivity of dexamethasone and methylphenidate in cancer patient who have fatigue
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
- Registration Number
- CTRI/2024/04/065257
- Lead Sponsor
- il
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Age 18 and above
2. Registered in palliative care centre
3. Suffering from histologically diagnosed advanced cancer
4. Patient with cancer related fatigue score greater than or equal to 4 to 10 on Edmonton symptoms assessment scale
5. Patient giving written informed consent
1. Pregnant and lactating female
2. Known history of hypersensitive to study drugs
3. History of AIDS
4. History of surgery in the last 2 weeks
5. Abnormal T3,T4,TSH
6. Anemia (Hb less than9)
7. Known case of Diabetes mellitus, Hypertension
8. Severe renal impairment,
9. Severe liver impairment,
10. Significant disorder of bone marrow
11. Cardiac conduction defect.
12. Patient taking Antipsychotic, sedative- psychotropic drug. Atropine and its substitute
13. Non co-operative patient
14. Patients who were not able to answer the questionnaires
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.FatigueTimepoint: Change in fatigue score will be assessed i.e 1 st week and 2 nd week
- Secondary Outcome Measures
Name Time Method 1.Effect on appetite <br/ ><br>2.Effect on psychological symptoms <br/ ><br>3. Adverse eventsTimepoint: 1.change in appetite will be assessed i.e. baseline, 1st week,2 nd week <br/ ><br>2.change in effect of psychological symptoms will be assessed i.e. baseline, 1st week and 2nd week <br/ ><br>3. Adverse events will be assessed i.e baseline,1 st week,2 nd week