Neuromuscular Ultrasonography Assessment of Optic Nerve in Systemic Lupus Eryhematosus
Completed
- Conditions
- Optic Neuropathy
- Registration Number
- NCT05853003
- Lead Sponsor
- Amira M elSonbaty
- Brief Summary
assessing the role of neuromuscular ultrasound in optic nerve involvement in systemic lupus patients.
- Detailed Description
Evaluating the role of neuromuscular ultrasound in optic nerve involvement in systemic lupus patients.by measuring the diameter of optic nerve at certain site and comparing it to healthy subjects measurements and to asses NMUS ability to detect optic neuropathy in lupus patients in comparison to conventional techniques including opthalmologist evaluation and visual evoked potential
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
- Adult
- group of SLE patients, who fulfilled Systemic Lupus International Collaborating Clinics classification criteria for SLE (SLICC) with or without symptoms of optic neuropathy
- another group of apparently healthy subjects with no. history of chronic conditions
Exclusion Criteria
-
Any patient with optic neuritis due to causes other than lupus was excluded from the study: ex.
- Post traumatic neuropathy
- Purely degenerative neuropathy
- Diabetic neuropathy
- Toxic neuropathy
- Neuropathies related to infections
- Drug induced neuropathy e.g: quinine and some antibiotics, ethambutol
- Infections e.g. measles, mumps, Lyme disease, etc.
- Other Autoimmune diseases like sarcoidosis, B.D
- Tumor causing Inc. intracranial tension.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method comparing diameter (in mm2) of optic nerve in SLE patients and compare them to healthy subjects over 1 year comparing diameter (in mm2) of optic nerve in SLE patients and compare them to healthy subjects
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Assuit university hospital
🇪🇬Assiut, Egypt