Comparison of Calcium EDTA and succimer in treating patients being intoxicated with lead by taking oral opium
Phase 3
- Conditions
- ead toxicity.Toxic effects of lead and its compounds
- Registration Number
- IRCT20180131038581N1
- Lead Sponsor
- Bandare-abbas University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 88
Inclusion Criteria
The presence of intoxication symptoms
Oral ingestion of opium
Laboratory confirmation of lead poisoning
Exclusion Criteria
Dissatisfaction to participate in the study
Presence of other causes for patient symptoms
Contact with a substance other than opium
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ead level. Timepoint: Before treatment, 5 days after treatment, and 2 weeks after treatment. Method of measurement: Clinical symptoms and blood test.
- Secondary Outcome Measures
Name Time Method Abdominal pain. Timepoint: Before treatment, 5 days after treatment and 2 weeks after treatment. Method of measurement: Questionnaire.;Constipation. Timepoint: Before treatment, 5 days after treatment and 2 weeks after treatment. Method of measurement: Questionnaire.;Systolic blood pressure. Timepoint: Before treatment, 5 days after treatment and 2 weeks after treatment. Method of measurement: Sphygmomanometer.;Diastolic blood pressure. Timepoint: Before treatment, 5 days after treatment and 2 weeks after treatment. Method of measurement: Sphygmomanometer.;Creatinine clearance. Timepoint: Before treatment, 5 days after treatment and 2 weeks after treatment. Method of measurement: Blood test.;Hemoglobin level. Timepoint: Before treatment, 5 days after treatment and 2 weeks after treatment. Method of measurement: Blood test.;Levels of liver enzymes. Timepoint: Before treatment, 5 days after treatment and 2 weeks after treatment. Method of measurement: Blood test.