Efficacy and safety of general anesthetics

Not Applicable

Recruiting

• Conditions: Scheduled non-cardiac surgeries under general anesthesia

• Registration Number: JPRN-jRCTs061230049
• Lead Sponsor: Miyoshi Hirotsugu

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-17
• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

1. Patients undergoing scheduled non-cardiac surgeries under general anesthesia
2. Patients aged 18 to 80
3. Patients with ASA-PS classification 1 or 2
4. Patients with BMI 18.5 to 30
5. Patients who can understand our explanation well enough, agree and sign the consent forms of their own will

Exclusion Criteria

1. Patients with heavy use of alcohol (over 60 g per day)
2. Patients who have or previously had an addiction to alcohol or any other drugs
3. Patients with common use of benzodiazepines
4. Patients with acute angle-closed glaucoma, myasthenia gravis or hypersensitivity to remimazolam
5. Patients with severe mental disorders
6. Patients with encephalopathy
7. Patients who are pregnant or lactating
8. Researchers who are directly involved in this study or other clinical studies, or their families
9. Patients who are judged inappropriate for this study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The time from administration of general anesthetics to loss of consciousness (seconds)

Secondary Outcome Measures

Name	Time	Method
The rate of change in blood pressure and heart rate during induction of general anesthesia