Sodium Bicarbonate Supplementation in Athletes
- Conditions
- SupplementationSport
- Interventions
- Dietary Supplement: Sodium bicarbonate supplementationDietary Supplement: Placebo treatment
- Registration Number
- NCT03165357
- Lead Sponsor
- Poznan University of Life Sciences
- Brief Summary
The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
- Detailed Description
Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive- dose NaHCO3 ingestion on physical capacity, body composition and concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 26
- written consent to participate,
- a current medical clearance to practice sports,
- training experience: at least 2 years (of CrossFit training),
- minimum of 3 workout sessions (CrossFit) a week,
- 20-43 years.
- current injury,
- any health-related contraindication,
- declared general feeling of being unwell,
- unwilling to follow the study protocol.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Sodium bicarbonate Sodium bicarbonate supplementation Group taking oral NaHCO3 supplementation in a progressive-dose regimen. Interventions: The experimental procedure for each athlete included a 10-day NaHCO3 supplementation in a progressive-dose regimen in order to reduce the likelihood of gastrointestinal side effects (from 37.5 to 150 mg ∙ kg-1). NaHCO3 was administered in the form of unmarked disk-shaped tablets (Alkala T, SANUM, Poland). The tablets were ingested with at least 250 mL of water and could be either swallowed or dissolved in the mouth. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening. Between the 10-day NaHCO3 and PLA or a PLA and NaHCO3 treatments, a 14-day washout period was introduced. Placebo (maltodextrin) Placebo treatment Group taking oral supplementation with placebo (maltodextrin). Interventions: The experimental procedure for each athlete included a 10-day placebo administration. Placebo was ingested with at least 250 mL of water. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening. Between the 10-day NaHCO3 and PLA or a PLA and NaHCO3 treatments, a 14-day washout period was introduced.
- Primary Outcome Measures
Name Time Method Changes in aerobic capacity after sodium bicarbonate supplementation Baseline and after 10 days The incremental cycling test (ICT)
Changes in specific performance capacity after sodium bicarbonate supplementation Baseline and after 10 days The CrossFit-specific physical fitness test: Fight Gone Bad (FGB)
- Secondary Outcome Measures
Name Time Method Changes in fat mass and fat free mass after sodium bicarbonate supplementation Baseline and after 10 days Fat mass (kg) and fat free mass (kg) analysis
Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementation Baseline and after 10 days Red blood cells (RBC) \[mln/mm³\] and white blood cells (WBC) \[mln/mm³\] concentration analysis
Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementation Baseline and after 10 days Hemoglobin (Hb) \[g/dl\] and glucose \[g/dl\] concentration analysis
Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementation Baseline and after 10 days Lactate \[mmol/L\] and pyruvate \[mmol/L\] concentration analysis
Changes in blood hematocrit levels after sodium bicarbonate supplementation Baseline and after 10 days Hematocrit (HCT) \[%\] level analysis
Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementation Baseline and after 10 days Creatine kinase \[U/L\] and lactate dehydrogenase \[U/L\] activity analysis
Trial Locations
- Locations (1)
Poznan University of Life Sciences, ul.Wojska Polskiego 31
🇵🇱Poznań, Wielkopolska, Poland