NCT01057303
Completed
Not Applicable
EVI-1 Expression in Pediatric AML With 11q23 Abnormalities
ConditionsLeukemia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Leukemia
- Sponsor
- Children's Oncology Group
- Enrollment
- 20
- Primary Endpoint
- Quantification of the expression of EVI1 splice variants
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research study is looking at gene expression in tissue samples from young patients with acute myeloid leukemia.
Detailed Description
OBJECTIVES: * Examine mRNA from pediatric patients with acute myeloid leukemia with 11q23 translocations by reverse transcriptase-PCR to quantify expression of EVI1 splice variants. OUTLINE: Cryopreserved mRNA from diagnostic samples is analyzed for gene expression by reverse transcriptase-PCR.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Quantification of the expression of EVI1 splice variants
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