NCT01229124已完成不适用
SCOR in Targeted Therapies for Infant Leukemias Project 4: MicroRNA Sequencing of Infant AML
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 主要终点
- Comparison of microRNAs present in infant AML samples to infant acute lymphoblastic leukemia samples to identify lineage- and translocation-specific microRNAs
研究概览
简要总结
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in RNA and identify biomarkers related to cancer.
PURPOSE: This research study is studying RNA biomarkers in tissue samples from infants with acute myeloid leukemia.
详细描述
OBJECTIVES:
- Sequence the microRNAs present in 20 infant AML samples as a pilot study.
- Compare microRNAs present in infant AML samples to infant ALL samples that are being concurrently sequenced in a separate study to identify lineage- and translocation-specific microRNAs.
OUTLINE: This is a multicenter study.
Previously collected cryopreserved cells from diagnosis are sequenced using reverse transcriptase-PCR.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 1 Year（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Comparison of microRNAs present in infant AML samples to infant acute lymphoblastic leukemia samples to identify lineage- and translocation-specific microRNAs
Sequence of the microRNAs present in 20 infant acute myeloid leukemia (AML) samples
次要结局
未报告次要终点
研究者
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