NCT01342783已完成不适用
Next Generation Sequencing of Childhood Soft Tissue Sarcomas to Identify Drivers of Primary and Metastatic Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 主要终点
- Occurrence of somatic mutations in driver genes and mutations in other genes that occur individually
研究概览
简要总结
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
PURPOSE: This research trial is studying biomarkers in samples from young patients with soft tissue sarcoma.
详细描述
OBJECTIVES:
- To identify the key components of driver pathways of primary and secondary soft tissue sarcomas.
- To perform the next-generation sequencing on primary versus normal on undifferentiated sarcomas.
OUTLINE: Genomic DNA and RNA samples from undifferentiated sarcoma tumors are analyzed by next-generation sequencing for somatic mutations. Normal matched lymphocytes and tissue are also analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Occurrence of somatic mutations in driver genes and mutations in other genes that occur individually
次要结局
未报告次要终点
研究者
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