The Effects of Serratus Anterior Plane Block on Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery

Not Applicable

Completed

• Conditions: Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
• Interventions: Drug: Ropivacaine; Drug: Normal Saline

• Registration Number: NCT02311517
• Lead Sponsor: Yonsei University

Brief Summary

Postoperative pain still remains a challenging problem in patients undergoing video-assisted thoracoscopic surgery (VATS). However, there is no gold standard for regional analgesia for VATS. Serratus anterior plane block (SPB) under ultrasound guidance has been described recently to achieve complete paresthesia of the hemithorax. Therefore, SPB has the possibility to provide analgesia following thoracic surgery. Pain following surgery is a critical side effect of surgery, which increases the risk of complications and delays a recovery. Therefore, SPB may help not only reduce pain following VATS, but also increase the quality of recovery. This study aims to investigate the effectiveness of ultrasound-guided SPB on the quality of recovery and pain in patients undergoing VATS.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-28
• Study First Submitted: 2014-12-04
• Study First Submitted QC: 2014-12-04
• Study First Posted: 2014-12-08
• Primary Completion: 2016-07-28
• Study Completion: 2016-07-28
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-14
• Last Update Posted: 2019-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

1. Adult patients (20-65 years of age) scheduled for elective video-assisted thoracoscopic surgery
2. ASA class I and II

Exclusion Criteria

1. Allergy to local anesthetics or contraindication to use of ropivacaine
2. Pregnancy
3. Neurologic and psychologic disease
4. Severe cardiovascular disease
5. Liver failure
6. Renal failure
7. Chronic treatment with analgesics

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ropivacaine group	Ropivacaine	45 patients will be randomly allocated into ropivacaine group with 0.4 ml/kg of 0.375% ropivacaine after induction of anesthesia.
saline group	Normal Saline	40 patients are randomly allocated into saline group with 0.4 ml/kg saline after induction of anesthesia.

Primary Outcome Measures

Name	Time	Method
Quality of Recovery 40 score	24 hours after operation day

Trial Locations

Locations (1)

Severance Hospital; 🇰🇷 Seoul, Korea, Republic of