Serratus Anterior Plane Block for Pain Treatment After Video-Assisted Thoracoscopic Surgery

Not Applicable

Completed

• Conditions: Nerve Block
• Interventions: Procedure: Serratus Anterior Plane Block; Drug: IV patient-controlled analgesia (PCA) tramadol

• Registration Number: NCT03217292
• Lead Sponsor: Bursa Yüksek İhtisas Education and Research Hospital

Brief Summary

Analgesia following video-assisted thoracoscopic surgery (VATS) is important for the prevention of postoperative pulmonary complications.Various regional methods of anesthesia are currently being used to achieve this goal. The aim of the study was to assess the effectiveness of SAPB on postoperative VATS analgesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-07-01
• Primary Completion: 2016-12-01
• Study Completion: 2016-12-01
• Status Verified: 2017-07
• Study First Submitted: 2017-07-02
• Study First Submitted QC: 2017-07-11
• Last Update Submitted: 2017-07-13
• Study First Posted: 2017-07-14
• Last Update Posted: 2017-07-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class and underwent video-assisted thoracoscopic surgery (VATS).

Exclusion Criteria

• Previous history of opioid use preoperatively,
• Allergy to local anesthetics,
• The presence of any systemic infection,
• Uncontrolled arterial hypertension,
• Uncontrolled diabetes mellitus.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group S	Serratus Anterior Plane Block	IV patient-controlled analgesia (PCA) tramadol+Serratus Anterior Plane Block(SAPB) Tramadol infusion (PCA): 400 mg tramadol, IV 4 mg/mL tramadol solution into 100 mL normal saline; PCA settings: 0.3 mg/kg bolus, 10 mg Demand dose and 20 min lock out interval, six-hour limit infusion to attain 100 mg. Maximum daily dose was set at 400 mg. 20 mL of bupivacaine at a concentration of 0.25% to between serratus anterior and intercostal muscle using the in-line technique for SAPB.
Group S	IV patient-controlled analgesia (PCA) tramadol	IV patient-controlled analgesia (PCA) tramadol+Serratus Anterior Plane Block(SAPB) Tramadol infusion (PCA): 400 mg tramadol, IV 4 mg/mL tramadol solution into 100 mL normal saline; PCA settings: 0.3 mg/kg bolus, 10 mg Demand dose and 20 min lock out interval, six-hour limit infusion to attain 100 mg. Maximum daily dose was set at 400 mg. 20 mL of bupivacaine at a concentration of 0.25% to between serratus anterior and intercostal muscle using the in-line technique for SAPB.
Group T	IV patient-controlled analgesia (PCA) tramadol	IV patient-controlled analgesia (PCA) tramadol Tramadol infusion (PCA): 400 mg tramadol, IV 4 mg/mL tramadol solution into 100 mL normal saline; PCA settings: 0.3 mg/kg bolus, 10 mg Demand dose and 20 min lock out interval, six-hour limit infusion to attain 100 mg. Maximum daily dose was set at 400 mg.

Primary Outcome Measures

Name	Time	Method
Visual Analogue Scale	Postoperative 24 hours	Visual Analogue Scale was used for pain

Secondary Outcome Measures

Name	Time	Method
tramadol consumption	Postoperative 24 hour	tramadol consumption
Ramsay sedation scale (RSS)	24 hours	Ramsay sedation scale (RSS)