Deliberate breathing training - Evaluation of a respiration-focused intervention program targeting psychological and biological mechanisms of depression and anxiety

Not Applicable

• Conditions: depressionanxiety; F30-F39; Mood [affective] disorders

• Registration Number: DRKS00023429
• Lead Sponsor: Zentralinstitut für Seelische Gesundheit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

current depression (DSM5), at least 18 years old, BMI 18-30

Exclusion Criteria

taking part in parallel training programs which also have a focus on breathing, such as yoga, pilates, tai chi, mindfulness, meditation, etc., or people who have had longer experience within the last three years

acute infections

persistent respiratory or lung diseases (FEV1/FVC < 0.7 (70%) or FVC or FEV1 below 70%)

MRI exclusion criteria (e.g. metal in the body), for MRI age 21-61

Crohn's disease, ulcerative colitis, endometriosis and similar diseases with possible adhesions in the abdominal cavity (influence on breathing mechanics)

previous severe chest injuries and operations in the chest area, as well as congenital changes to the chest (e.g. funnel chest) and acute severe heart disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
depression scores and mood (various questionnaires and MADRS as external assessment), anxiety values (various questionnaires)<br>collected in each case before and after the training, as well as with half of the group before a 2-month waiting period and with the other half at a 2-month follow-up

Secondary Outcome Measures

Name	Time	Method
respiratory Variability (RPV) parameters (e.g. PD CV, AZV), body perception (questionnaires and heart beat detection task), neural correlates (e.g. PCC - parahippocampal connectivity)<br>collected in each case before and after the training, as well as with half of the group before a 2-month waiting period and with the other half at a 2-month follow-up (no MRI at follow up)