The blood concentration of acetaminophenin and analgesic effect

Phase 1

• Conditions: Post operative pain; acetaminophen, predicted cerebrospinal fluid concentration, pain threshold

• Registration Number: JPRN-jRCTs031200034
• Lead Sponsor: ishimura Akiko

Brief Summary

There was a greater variation between subjects than expected about minimum sense current, which is the main evaluation item,so it was judged that it is difficult to evaluate the analgesic effect about acetaminophen.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-19
• Study Completion: 2020-06-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 7

Inclusion Criteria

Volunteers who understand about this study and give informed consent with free will

Exclusion Criteria

1) Patients who use cardiac pacemaker device
2) Expectant or nursing mothers
3) Patients who have severe hepatic impairment
4) Patients who have allergy to acetaminophen
5) Patients who have peptic ulcer
6) Patients who have hematological disorder
7) Patients who have severe kidney impairment
8) Patients who have severe cardiac dysfunction
9) Patients who have aspirin asthma

Study & Design

• Study Type: Interventional
• Study Design: Not specified