Relation between intraluminal intensity of blood speckle on intravascular ultrasound and fractional flow reserve

Not Applicable

• Conditions: Coronary artery disease

• Registration Number: JPRN-UMIN000026325
• Lead Sponsor: Chiba University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-01
• Study Completion: 2021-12-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients with hemodialysis 2) Patients who use nhaled drugs or theophylline products for bronchial asthma 3) Patients with left main trunk lelsion or stenosis >50% at the distal to the target lesion. 4) Patients with chronic total obstruction 5) Patients with severe heart failure (ejection fraction <30% or NYHA >class 3) 6) Patients with prior coronary artery bypass grafting

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison between the difference in intraluminal intensity of blood speckle (Delta IBS) and fractional flow reserve (FFR) with or without hyperemia.

Secondary Outcome Measures

Name	Time	Method
1) Comparison between Delta IBS and instantaneous wave-free ratio (iFR) with or without hyperemia. 2) Diagnostic Accuracy of Delta IBS for physiological assessment of coronary artery stenosis by FFR with or without hyperemia. 3) Diagnostic Accuracy of Delta IBS for physiological assessment of coronary artery stenosis by iFR with or without hyperemia. 4) Diagnostic Accuracy of minimum lumen area (MLA) on intravascular ultrasound (IVUS) for physiological assessment of coronary artery stenosis.