CTRI/2020/12/029534Not yet recruiting未知
A cross-sectional study on impact of CYP2C8 and CYP3A4 activity on pharmacokinetic variability of paclitaxel in chemotherapy naïve cancer patients
All India Institute of Medical Sciences Rishikesh0 sites0 target enrollmentStarted: TBDLast updated:
Trial Snapshot
- Phase
- 未知
- Status
- Not yet recruiting
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •All chemotherapy naïve patients of malignancy.
- •Patients of malignancy planned to be treated with paclitaxel.
- •Patients of malignancy considered fit for chemotherapy will be enrolled in this study
- •Patients above 18 years of age
- •Patients willing to provide written informed consent
Exclusion Criteria
- •Deranged renal function (serum creatinine level >= 1.5 mg/dL),
- •Concomitant radiotherapy for primary or metastatic sites;
- •Any other drugs known to induce or inhibit CYP3A4 or CYP2C8 enzyme
Investigators
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