Effects of renal dysfunction and sleep apnea on ambulatory blood pressure profile, cardiovascular function, and glucose and lipid metabolism: cross-sectional and prognosis study.
Not Applicable
- Conditions
- Hypertensionj
- Registration Number
- JPRN-UMIN000000667
- Lead Sponsor
- Yokohama City University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
Not provided
Exclusion Criteria
acute myocardial infarction, collagen disease, acute renal failure
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) casual blood pressure 2) ambulatory blood pressure monitoring 3) sleep apnea test 4) renal function: creatinine clearance by Cockcroft-Gault formula 5) glucose metabolism: fasting blood glucose, fasting IRI, HOMA-IR 6) lipid metabolism: total cholesterol, LDL, HDL, TG, adiponectin 7) cardiac function: ANP, BNP, UCG 8) vascular function: ABI/BWV, carotid echogram 9) sympathetic nerve activity and renin-angiotensin system 10) inflammatory and oxidative markers: CRP, fibrinogen, MDA-LDL, AGE.
- Secondary Outcome Measures
Name Time Method