Comparison of hemodynamic index and duration of effect of two drugs, bupivacaine and ropevacaine during spinal and epidural analgesia in orthopedic lower extremity surgery and umbilical cord surgery (T8 level)
Not Applicable
- Conditions
- Condition 1: Spinal T8 level. Condition 2: T8 level analgesic epidural.
- Registration Number
- IRCT20210218050400N1
- Lead Sponsor
- Birjand University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients referred to Imam Reza Hospital who underwent lower limb orthopedics and umbilical cord surgery without underlying disease,
using a tourniquet
without bleeding and operation time less than 1 hour and 45 minutes
Exclusion Criteria
People with any underlying disease, people who have a ban on spinal anesthesia (such as coagulation disorders, infection at the site of anesthesia
and unwillingness to anesthetize
hypovolemia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Blood pressure monitor.;Blood oxygen level. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Pulse oximetry.;Duration of anesthesia. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Based on sensory level.;Intensity of sensory block. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Based on sensory level.;The effectiveness of drugs. Timepoint: Intervals of 5 minutes for the first 30 minutes after injection. Method of measurement: Using 100 mm analog pain scores (VAPS).
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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What are the molecular mechanisms by which bupivacaine and ropivacaine affect hemodynamic stability during spinal and epidural analgesia?
How does the efficacy of bupivacaine compare to ropivacaine in T8-level analgesia for lower extremity and umbilical surgeries?
Are there specific biomarkers that predict prolonged analgesic duration with ropivacaine versus bupivacaine in orthopedic procedures?
What adverse events are associated with bupivacaine and ropivacaine at T8 spinal and epidural levels in surgical settings?
How do bupivacaine and ropivacaine compare to other local anesthetics in managing postoperative pain for lower abdominal and lower limb surgeries?