Functional and structural brain problems underlying language development disorders in preterm children followed up at age 9

Completed

• Conditions: language and speech development; communication disorder; language development disorders; 10028920

• Registration Number: NL-OMON46275
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 134

Inclusion Criteria

For preterm subjects (N<=60): Children and their parents participated in the study by van Noort-van der Spek [MEC-2012-149], and parents gave permission to contact them in the future for scientific research, in their last contact moment.
One parent of each participating preterm child (N<=50): the parent that is accompanying the child at the day of testing has to give permission to participate in a language subtest himself/herself.;For term-born control children (N<=24): Children must be born at term age (>37 weeks of gestation) and an individual child must be matched to one of the preterm subjects with in respect to age, gender and education level of the mother.

Exclusion Criteria

Participants (preterm-born and term-born) with a permanent (sensorineural) hearing loss from >20 dB at the best ear, measured with pure tone audiometry, will be excluded from participation.;Exclusion criteria for making the MRI scan in the optional additional visit are:
(1) Non-removable non-MRI compatible implants;
(2) Claustrophobia

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main outcome measure is the Core language score measured by the Clinical<br /><br>Evaluation of Language Fundamentals-4 (CELF).</p><br>