A Comparison of Protein-bound and Large Molecular Weight Uremic Toxin Removals With Novel Super High-flux Dialyzer Between Hemodialysis and High Volume Online HDF Modalities
Not Applicable
Completed
- Conditions
- UremicToxemia
- Registration Number
- NCT06567483
- Lead Sponsor
- Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Inclusion Criteria:<br><br> - Chronic hemodialysis patients in King Chulalongkorn Memorial hospital<br><br> - Residual renal function less than 100 ml/day<br><br>Exclusion Criteria:<br><br> - Dialyzer allergy<br><br> - Malnutrition requiring intradialytic parenteral nutrition<br><br> - Cirrhosis child C or decompensated cirrhosis<br><br> - Active uncontrolled infection<br><br> - Active cardiovascular disease<br><br> - Advanced stage malignancy<br><br> - Predicted to be undergone living related kidney transplant within 1 year
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Protein bound uremic toxin reduction ratio (percent)
- Secondary Outcome Measures
Name Time Method Beta2 microglobulin, kappa and lambda free light chain and urea reduction ratio (percent);Serum albumin and dialysate albumin loss;Quality of life assessment in each group