Ecological Assessment of Apathy in Alzheimer's Disease and in Control Subjects: Interest on Video Recognition and Actigraphy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Alzheimer Disease
- Sponsor
- Centre Hospitalier Universitaire de Nice
- Enrollment
- 82
- Locations
- 1
- Primary Endpoint
- stride and speed walking
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
Cognitive and memory disorders are characterized of Alzheimer disease. In addition, psychologic and behavioural symptoms, called speak neuropsychiatric symptoms, are frequents and play an important role in prognostic and intervention. These symptoms are noticed before the diagnostic of dementia, their prevalence and their intensity increase with the evolution of disease. Apathy, which is characterized by a decrease of motivation, is the most frequent of this behaviour disrupt. Clinically, a decrease, or a totally, lack of interest, initiative and blunting emotional are noticed. Fundamentally, apathy is considered as a decrease of cognition and behaviour to "go in goal". Assessment of psychological and behavioural symptoms is realised principally with neuropsychiatric scales. These contribute to obtain particular informations about health of patient allowing by patient and caregiver discussions and impressions of clinician. These scales are simples but loss of subjectivity. An alternative of this method is the use of gerontechnology as actigraphy (system out-patient which records locomotive activity with the help of piezo-electrical sensor fixed on a bracelet) and video recording which is associated to an informatic treatment of signal in order event recognition.
The aim of study is to realise an objective assessment of activities "go in goal" during experimental sequence which has well-characterized acts, using at the same time an actigraphic record of activity "motive" (system of assessment indirect of apathy fit) and a video records which uses an informatic event recognition system. The assessment will realise with participants controls (n=30) and Alzheimer disease patients with (n=20) or without (n=20) apathy, during well-characterized records. The final aim is to obtain a particular assessment of some disorders behaviours, as apathy, which is principally characterize by a decrease of behaviours "to go in goal".
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Impossibility of realization of the experimental protocol because of a driving handicap.
- •Port(Bearing) of a pacemaker
- •Under guardianship Patient or guardianship
Outcomes
Primary Outcomes
stride and speed walking
Time Frame: one time point - at the only visit of protocol (day 1)
Secondary Outcomes
- For comparison between Alzheimer disease patients with (n=20) or without apathy, we use again stride and speed walking(one time point - at the only visit of protocol (day 1))
- For reproducibility, we use stride and speed walking(one time point - at the only visit of protocol (day 1))
- Reliability is the sum of posture's concordance(one time point - at the only visit of protocol (day 1))
- Relation between LF/HF variations and activity index(one time point - at the only visit of protocol (day 1))