The potential benefits of high and low carotenoid-rich fruits and vegetables on preserving skeletal muscle mass in overweight/obese older adults when placed on a weight loss diet.

Not Applicable

Recruiting

• Conditions: Obesity; Ageing; Body Composition Assessment; Sarcopenia and Frailty; Diet and Nutrition - Obesity

• Registration Number: ACTRN12616001400459
• Lead Sponsor: Dr Anthony Villani

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-10-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Community-dwelling older adults over the age of 60 years
Overweight or obese (BMI greater than 27kg.m2)
Otherwise healthy

Exclusion Criteria

BMI less than 27kg.m2
Reside in high level residential care
Dementia or cognitive impairment
Type 2 diabetes (medicated with insulin)
Cancer
Renal or liver disease
Unstable CVD
Neurological disease
Current use of anti-inflammatory or corticosteroid medications
Current involvement in a secondary study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Body Composition (skeletal muscle mass; fat-free mass; fat-mass) assessed using Dual-Energy X-Ray Absorptiometry (DEXA) [Baseline and 12-weeks];Muscle Strength assessed as grip-strength using a hand-held dynamometer [Baseline and 12-weeks];Physical performance assessed using the Physical Performance Battery (balance, timed sit-to-stand and usual gait speed) [Baseline and 12-weeks]

Secondary Outcome Measures

Name	Time	Method
Quality of Life assessed using the 36-item Short Form health instrument (SF-36) [Baseline and 12-weeks];Physical activity status assessed using the International Physical Activity Questionnaire (IPAQ)[Baseline and 12 weeks];Adherance to a Mediterranean dietary pattern assessed using the 14-item Mediterranean Diet Questionnaire[Baseline only]