NL-OMON47114
Completed
Not Applicable
Inflammatory markers in Broncho-alveolar Lavage fluid as risk factors for Lung disease in infants with Cystic Fibrosis: the I-BALL study - I-BALL study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects are eligible for this study when:
- •\- They are diagnosed with CF, confirmed with 2 mutations found by genetic analysis, either from heel prick screening or diagnosed later in life.
- •\- Aged 1, 3 or 5 years, when they will undergo bronchoscopy and chest CT scan as part of the routine monitoring program for CF.
- •\- Authorized by an informed consent from parents to undergo a possible extra rinse during bronchoscopy to retrieve sufficient BALF, an extra blood sample of 2 ml during the routine venous puncture, and permission to use excess biomaterials and coded clinical data for research.
Exclusion Criteria
- •Absence of previously given informed consent for use of encoded clinical data for scientific purposes
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Diagnostic value of bronchial washings in suspected sputum negative pulmonary tuberculosisCTRI/2020/01/022645Dr Khushboo Chahwala
Completed
Not Applicable
se of bronchoalvelair lavage enzymlinked immunospot as a diagnostic measurement of bird fancier's lung.bird fanciers lungextrinsic allergic alveolitis1000170810024967NL-OMON34215Diakonessenhuis Utrecht20
Completed
Not Applicable
Assessment of inflammatory response of bronchial cells to gastric juice from hospitalized infants on and off proton pump inhibitor (PPI) therapy, PICU admitted children and long term users (0-18 years) of PPIs and controls off PPIgastroesophageal reflux/heartburn - microaspiration induced respiratory tract infections/airway infections due to reflux in airway1001797710024970NL-OMON39158Academisch Medisch Centrum90
Active, not recruiting
Not Applicable
Biomarkers in respiratory immunologyISRCTN45524058iverpool School of Tropical Medicine500
Terminated
Phase 4
Cytokine Change in Bronchoalveolar Lavage Fluid After Early Budesonide-Surfactant Treatment in Premature InfantsPremature InfantsRespiratory Distress SyndromeChronic Lung DiseaseBronchoalveolar Lavage FluidCytokinesNCT00146497China Medical University Hospital30