Validation of Photoplethysmography Device for the Measurement of Aortic Pulse Wave Velocity Against Carotid-Femoral Values From Piezoelectric Sensors
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aortic Pulse Wave Velocity
- Sponsor
- VitalSines International Inc.
- Enrollment
- 180
- Primary Endpoint
- Aortic Pulse Wave Velocity
- Last Updated
- 3 years ago
Overview
Brief Summary
Existing techniques available for capturing reliable aortic pulse wave velocity measurements and estimating aortic stiffness are costly and require technical expertise. The purpose of this research is to investigate an oximeter device performance as a stand-alone aortic pulse wave velocity (PWV) measurement instrument. By validating this device and its measurements against the gold-standard method of carotid-femoral readings, we aim to demonstrate that the proposed method is an comparably effective in terms of the metrics (Mean difference, standard deviation, correlation, etc.) outlined by the Artery Society Guidelines.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •History of cardiovascular disease
- •Not in sinus rhythm/arrhythmia
- •Pacemaker
- •Impalpable arterial pulse
- •Use of blood pressure medication
- •Systolic blood pressure \> 140
- •Use of vasoactive medication
- •Use of cholesterol medication
- •Diabetes diagnosis
- •BMI \> 30 kg/m2
Outcomes
Primary Outcomes
Aortic Pulse Wave Velocity
Time Frame: 6 measurements per subject, each lasting 60 seconds
The speed at which a single pulse/heart beat propagates down the aorta.