Validation of Indicor Photoplethysmography (PPG) Valsalva Pulse Response vs Non-invasive Blood Pressure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Failure
- Sponsor
- Vixiar Medical, Inc.
- Enrollment
- 121
- Locations
- 1
- Primary Endpoint
- pulse amplitude ratio
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
This study designed is compare the pulse response to the Valsalva maneuver between a photoplethysmography sensor (PPG) and non-invasive blood pressure sensor for the purpose of validating the PPG methodology in deriving a value for the Valsalva pulse response. The aim is to show that the PPG method captures the same phase responses as the blood pressure monitor and the primary outcome is the correlation between pulse amplitude ratios for the pulse at the end of the Valsalva to an average baseline pulse.
Detailed Description
With both a photoplethysmography (PPG; Indicor, Vixiar Medical,. Baltimore, MD) and non-invasive blood pressure (Caretaker, Caretaker Medical, Charlottesville, VA) sensors in place on the index and middle fingers, respectively, each patient will be asked to perform three mild, 10-sec Valsalva maneuvers with at least 45 seconds between. Pulse recordings will be collected from each device to compare phases of the Valsalva pulse response including pulse amplitude changes and baseline movement. The primary outcome is the correlation between pulse amplitude ratios for the pulse at the end of the Valsalva to an average baseline pulse.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Clinically stable adults, including heart failure patients visiting an outpatient clinic
Exclusion Criteria
- •Atrial flutter or atrial fibrillation with an irregular ventricular response
- •Significant atrial or ventricular ectopy
- •History of paradoxical emboli
- •Hypertrophic obstructive cardiomyopathy
- •Known intracardiac shunt
- •Known severe aortic valve stenosis
- •Known severe mitral valve stenosis
- •History of embolic CVA
- •Myocardial infarction within one week of intended Indicor testing
- •Uncontrolled hypertension (systolic BP \>160mmHg or diastolic BP\>100mmHg)
Outcomes
Primary Outcomes
pulse amplitude ratio
Time Frame: 5 minutes
The correlation between PPG-based and non-invasive blood pressure pulse amplitude ratio during a Valsalva maneuver.
Secondary Outcomes
- Phases of valsalva pulse response(5 minuntes)