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Clinical Trials/NCT04092946
NCT04092946
Completed
N/A

Home-based Digital Program for Musculoskeletal Disorders: a Large-scale, Multi-disorder, Prospective, Single-arm, Interventional Study

Sword Health, SA1 site in 1 country48,774 target enrollmentJune 16, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Musculoskeletal Diseases
Sponsor
Sword Health, SA
Enrollment
48774
Locations
1
Primary Endpoint
Neck Disability Index
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this study is to assess the acceptance, engagement and outcomes of a digital care program for acute and chronic musculoskeletal conditions affecting the shoulder, elbow, hip, knee, ankle and spine.

Detailed Description

SWORD Health has developed a novel digital biofeedback system for home-based physical rehabilitation - SWORD Phoenix- which is an FDA-listed class I medical device. The company has previously conducted two pilot studies (NCT03047252; NCT03045549) comparing a digital rehabilitation program using this device against conventional face-to-face physical therapy. These studies have proven the feasibility, safety and effectiveness of this medical device on rehabilitation after total knee and hip arthroplasty. SWORD Health is now seeking additional validation of its digital programs on acute and chronic MSK conditions, to assess the acceptance, engagement and outcomes of these clinical programs. This study will also unveil disease-specific human motion patterns that may be used to inform the development of new diagnostic and treatment tools. Data to be collected on every individual undergoing our programs includes: 1. data that is sourced from the subject through online assessment forms 2. data that is sourced from the subject, collected by the physical therapist managing that subject (i.e. suggestions for improvement); 3. data that is generated by the physical therapist through interaction with the web-based Portal (i.e. session composition in terms of exercises, sets, repetitions, usage or not of external resistance) 4. data generated by the patient through interaction with the mobile app (i.e. pain and fatigue levels, satisfaction) 5. data that is generated automatically by the medical device (i.e. range of motion, compliance) Collection and objective analysis of the collected data will allow: 1. Monitoring of user needs, engagement and satisfaction to guide further improvements; 2. Analysis of the effectiveness of these digital care programs; 3. Correlation of results with patient's demographic and clinical profiles; 4. Compilation of patient cohorts to increase and disseminate knowledge on each disorder, its progression and response to physical therapy programs; 5. Explore the cost-efficiency of these digital programs 6. Development of novel intelligent tools to assist therapists with patient management.

Registry
clinicaltrials.gov
Start Date
June 16, 2020
End Date
February 10, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Sword Health, SA
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Over 18 years old
  • Suffering from acute (\<12 weeks) or chronic (\>12 weeks) pain in the neck, low back, shoulder, elbow, hip, knee, ankle or wrist;
  • Able to understand study procedures and willing to provide informed consent

Exclusion Criteria

  • Cardiac or respiratory condition incompatible with at least 20 minutes of light to moderate exercise
  • Cancer diagnosis or receiving treatment for cancer
  • Unexplained weight loss in the last 6 months
  • Significant trauma in the area of pain in the last 3 months
  • Rapidly progressive loss of strength and/or numbness in the arms/legs in the last 2 weeks
  • Unexplained change in bowel or urinary function in the last 2 weeks
  • Other known health condition limiting participation in an exercise program involving at least 20 minutes of light to moderate exercise

Outcomes

Primary Outcomes

Neck Disability Index

Time Frame: Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment

Change in condition-specific clinical outcomes over time measured through the Neck Disability Index. The scores for all questions answered are summed, then multiplied by two to obtain the index (range 0 to 100). Zero is equated with no disability and 100 is the maximum disability possible.

Oswestry Disability Index

Time Frame: Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment

Change in condition-specific clinical outcomes over time measured through the Oswestry Disability Index (ODI). \\ The scores for all questions answered are summed, then multiplied by two to obtain the index (range 0 to 100). Zero is equated with no disability and 100 is the maximum disability possible.

Short version of the Disabilities of the Arm, Shoulder and Hand questionnaire

Time Frame: Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment

Change in condition-specific clinical outcomes over time measured through the short version of the Disabilities of the Arm, Shoulder and Hand questionnaire (QuickDASH). Scoring Formula = (\[(sum of n responses)/n\] -1)x(25).

Hip Disability and Osteoarthritis Outcome Score

Time Frame: Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment

Change in condition-specific clinical outcomes over time measured through the hip disability and osteoarthritis outcome score (HOOS) Scoring Formula: 100 - \[(patient's score of the subscale x 100)/(total score of the subscale)\]

Neck, lower spine, shoulder, elbow, ankle, hip and knee range of motion

Time Frame: Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment

Change in condition-specific clinical outcomes over time measured through Neck, lower spine, shoulder, elbow, ankle, hip and knee range of motion (ROM) (flexion/extension/abduction/rotation), in degrees, as directly retrieved from the angle measurement tool integrated within the medical device.

Foot and Ankle Ability Measure

Time Frame: Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment

Change in condition-specific clinical outcomes over time, measured through the Foot and Ankle Ability Measure (FAAM). FAAM is a self-report measure that assesses physical function of individuals with lower leg, foot, and ankle musculoskeletal disorders. Thus instrument included 2 subscales: 1) Activities of Daily Living (ADLs) with 21 items and 2) Sports with 8 items. For each subscale patients are asked to answer each question with a single response that most clearly describes their condition within past week. To calculate the score for either subscale, the total number of points are added, divided by the total number os possible points (ADLs-84; Sports-32) and then multiplied by 100.

Knee Injury and Osteoarthritis Outcome Score

Time Frame: Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment

Change in condition-specific clinical outcomes over time measured through the Knee Injury and Osteoarthritis Outcome Score (KOOS) Scoring Formula: 100 - \[(patient's score of the subscale x 100)/(total score of the subscale)\]

Secondary Outcomes

  • Self-reported Medication(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Self-reported Pain(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Self-reported Surgical Intent(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Depression(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Engagement levels(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Anxiety(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Fear avoidance behaviour(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Work Productivity and Absenteeism(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Satisfaction scores(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)
  • Completion rates(Baseline, each four weeks after initiation of rehabilitation program, and periodical follow-up assessments (each 8 weeks) until 2 years after enrolment)

Study Sites (1)

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