Cognitive changes related to anesthetic technique

Hospital Universitário Gaffree e Guinle0 sitesAugust 11, 2023

Overview

No summary available.

Registry

who.int

Start Date

August 11, 2023

End Date

May 1, 2025

Last Updated

2 years ago

Study Type

Intervention

Sponsor

Hospital Universitário Gaffree e Guinle

•Age above18 years; signing of the Free and Informed Consent Form about participation in the study; physical status ASA (American Society of Anesthesia) I; II and III ( one, two and three); patients undergoing general anesthesia for laparoscopic cholecystectomy and/or thyroidectomy; lasting less than 300 minutes. And control group with 60 patients not submitted to surgery.

•ASA(American Society of Anesthesia) scale four; presence of neurological or psychiatric disease affecting cognition; continuous use of: corticosteroids; antipsychotics; opioids, zolpiden; tricyclic antidepressants; smoking; alcoholism; severe liver disease; renal failure (creatinine clearance under 100\); inability to perform neuropsychometric tests independentes. The following perioperative situations exclude research participants: Postoperative delirium; report of anesthetic complications, including hypoxemia; hypotension and deep anesthetic plane (BIS (Bispectral Index Scale) under thirty five); report of general anesthesia up to one year prior to surgery; previous cardiac or neurological surgeries; urgent surgeries or with intraoperative surgical complications (bleeding and reoperation).