Serum Folic Acid and Vitamin B12 in children with Idiopathic Epilepsy and their relation to Seizure Control and Cognitive functions

Not Applicable

• Conditions: Paediatrics; idiopathic epilepsy

• Registration Number: PACTR201704002060106
• Lead Sponsor: faculty of medicine ain shams university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-02-22
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

1-Drug resistant epilepsy: failure of adequate trials of two or more tolerated, appropriately chosen and used AED schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom which is defined as freedom from all seizures, including auras, for at least three times the longest pre-treatment interseizure interval or 12 months.
2- Age: 5-18 years.

Exclusion Criteria

1-Neurological, endocrinal or any systemic disease other than epilepsy.
2- Symptomatic and cryptogenic epilepsy.
3- Nutritional status impairments. (Z score ¿ -2SD)
4- Intake of nutritional supplements like vitamins and minerals.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
decrease severity of epilepsy;decrease frequency of epilepsy;improve cognitive function test