Impact of Tooth Loss and Denture on Oral Senses and Food Preferences

Not Applicable

• Conditions: Tooth-loss
• Interventions: Procedure: Tooth removal and their replacement by means of a denture

• Registration Number: NCT04281056
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

Tooth loss impacts taste abilities and food intake. Present study aims at pertaining the impact of teeth loss and the replacement by means of complete denture on taste and trigeminal abilities, and on food preferences, and taste appetence.

Detailed Description

Two groups of participants will be included. Participants wearing complete denture for at least one year (n=20) and their matched controls for age, sex, tobacco, and saliva secretion (n=20). Their oral sensory abilities of participants will be assessed including taste (electrogustometric thresholds, chemical taste identification ability) and trigeminal quantitative sensory testing. Food preferences and selectivity (Maitre et al., 2014) and taste appetence (Deglaire et al., 2012) will also be assessed.

Study Timeline

• Status Verified: 2020-02
• Study First Submitted: 2020-02-20
• Study First Submitted QC: 2020-02-20
• Last Update Submitted: 2020-02-20
• Study First Posted: 2020-02-21
• Last Update Posted: 2020-02-21
• Study Start: 2020-07
• Primary Completion: 2020-07
• Study Completion: 2020-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Study Group : being completely edentulous and wearing denture for at least one year, wearing denture during meals, with clean and stable dentures. Controls:

controls Group : dentate subjects (25 teeth at leas, non endodontically treated) with molars in Angle's Class I occlusion, having no functional disturbance of mastication and not undergoing dental treatment at the time of the recording. Matched with subjects of the study group for age, sex, tabacco consumption, and saliva flow rate.

Exclusion Criteria

• Aged under 18 or over 80 Y,
• not consenting to participate
• suffering from dental
• periodontal or gum pain for the last month.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Tooth removal	Tooth removal and their replacement by means of a denture	Tooth removal and their replacement by means of a denture Teeth have been removed and replaced by means of dentures for at least one year

Primary Outcome Measures

Name	Time	Method
taste detection thresholds	up to 30 days	Using an Electrogustometer

Secondary Outcome Measures

Name	Time	Method
Chemical taste identification ability	up to 30 days	Using taste strips (Burghard)
Quantitative sensory testing	up to 30 days	Using an algometer, von frey filament, a thermode.
Food preferences and selectivity	up to 30 days	Questionnaire food selectyivity and preference (Maitre et al., 2014)
Taste appetence	up to 30 days	Questionnaire PrefQuest (Deglaire et al., 2012)

Trial Locations

Locations (1)

Service odontologie Hôpital Rothschild; 🇫🇷 Paris, France