Effect of Inspiratory and Expiratory Training on autonomic modulation, exercise capacity and pulmonary capacity of Chronic Obstructive Pulmonary Disease patients
Not Applicable
- Conditions
- Chronic Obstructive Pulmonary DiseaseJ44.9
- Registration Number
- RBR-4mz6w9
- Lead Sponsor
- niversidade Federal do Maranhão
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Data analysis completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Volunteers with the diagnosis of Chronic Obstructive Pulmonary Disease; who had inspiratory muscle weakness (70% of predicted maximal inspiratory pressure); with absence of heart failure; with stable pharmacological treatment; and with no comorbidity such as type 2 diabetes mellitus and hypertension.
Exclusion Criteria
Volunteers who had acute myocardial infarction three months before inclusion in the study; unstable ventricular arrhythmia or in the last three months before onset; acute respiratory disease; rheumatic diseases; degenerative diseases; neurological sequelae and cognitive deficit
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of 10% of maximal inspiratory and expiratory capacity and increase of forced vital capacity by 10%, measured by spirometry<br>;In the treatment group, an increase of 35% in inspiratory capacity and 28% in maximal expiratory pressure was found. Also, an 9% reduction in forced vital capacity was found.<br>
- Secondary Outcome Measures
Name Time Method Exercise tolerance, demonstrated by a 10% increase in the 6-minute Walk Test distance;In the treated group, a 32% increase in distance from the six-minute walk test was found.;Improved autonomic modulation, demonstrated by heart rate variability, with increased total variance of 20%;In the treated group, a 63% increase in total variance was found.<br>