Sequential Versus Single O2 Levels on Human Embryo Development

Not Applicable

Completed

• Conditions: Embryo Culture

• Registration Number: NCT03630900
• Lead Sponsor: Ibn Sina Hospital

Brief Summary

Myriads of elements affect human embryo culture in vitro. These include, but not limited to, air quality, culture media, culture temperature, incubator humidity, pH, and O2 levels. O2 tension has been thoroughly investigated and, to date, 5% O2 level is superior to 20%. Reports showed that lowering the O2 from Day 3 of embryo culture seems to be physiological.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-08-10
• Study First Submitted QC: 2018-08-10
• Study First Posted: 2018-08-15
• Study Start: 2018-08-24
• Primary Completion: 2019-06-20
• Status Verified: 2019-07
• Study Completion: 2019-07-01
• Last Update Submitted: 2019-07-14
• Last Update Posted: 2019-07-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 487

Inclusion Criteria

• ICSI cycles undergoing their first ICSI attempt

Exclusion Criteria

• ICSI cycles with a previous failure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Ongoing Implantation rate	three months	number of sacs with a heartbeat after week twelve of gestation

Secondary Outcome Measures

Name	Time	Method
human embryo development in vitro	three months
clinical and ongoing pregnancies	three months	registered pregnancy with fetal heartbeat at week four after transfer and after week twelve of gestation

Trial Locations

Locations (3)

Banon Assiut; 🇪🇬 Assiut, Egypt

Qena Fertility Center; 🇪🇬 Qena, Egypt

IbnSina IVF Center; 🇪🇬 Sohag, Egypt