Oxygen Portable Concentrator During Exercises in Patients With COPD

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Device: Oxygen concentrators versus constant flow axygen; Device: oxygen concentrator

• Registration Number: NCT00875719
• Lead Sponsor: Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche

Brief Summary

The purpose of this study is to compare differences in oxygen delivery between portable oxygen concentrators (POCs) and liquid oxygen (LOs) portable units, pose a question if POCs are equally effective as LOs in reducing exercise-induced hypoxaemia. DESIGN: Randomized, single-blind clinical trial.

Detailed Description

Our primary objective is to compare at rest and during exercise the evolution of oxygen saturation and dyspnea during 6 minutes walking test in patients with COPD receiving oxygen supplementation either with portable concentrators or liquid oxygen in a random order.

Study Timeline

• Study Start: 2009-02
• Study First Submitted: 2009-03-27
• Study First Submitted QC: 2009-04-02
• Study First Posted: 2009-04-03
• Primary Completion: 2011-01
• Status Verified: 2011-02
• Study Completion: 2011-02
• Last Update Submitted: 2011-02-15
• Last Update Posted: 2011-02-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• COPD with respiratory failure and indication for oxygen supplementation at rest and/or during exercice.

Exclusion Criteria

• Evolutive heart disease.
• Unability to understand or realize the tests.
• Acute exacerbation during the last month.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
continuous v intermittent Oxygen therapy	oxygen concentrator	intermittent oxygen compared to constant flow oxygen as regards walking distance
continuous v intermittent Oxygen therapy	Oxygen concentrators versus constant flow axygen	intermittent oxygen compared to constant flow oxygen as regards walking distance

Primary Outcome Measures

Name	Time	Method
Oxygen Saturation	One day

Secondary Outcome Measures

Name	Time	Method
Walking Distance	One day

Trial Locations

Locations (1)

Service de Pneumologie et Allergologie- Hôpital le Cluzeau. 23 av. D. Larrey; 🇫🇷 LIMOGES cedex, France